Transcriptomics

Dataset Information

300

Transcriptome sequencing of skeletal muscle for PRMT7 knockout mouse


ABSTRACT: We report that whole body PRMT7-/- adult mice display a significant reduction in in muscle mass. RNA sequencing was performed to identify potential PRMT7 targets. We found that top canonical pathways affected by the loss of PRMT7 includes cell cycle and senescence. RNA was extracted from tibialis anterior muscles harvested from 3 WT and 3 PRMT7 null mice at 8months. RNA sequencing was performed to compare mRNA in skeletal muscles between WT and KO mice.

ORGANISM(S): Mus musculus  

SUBMITTER: Romeo Blanc   Taiping Chen  Stéphane Richard  Roméo Blanc  Gillian Vogel 

PROVIDER: E-GEOD-75993 | ArrayExpress | 2016-07-03

SECONDARY ACCESSION(S): SRP067359GSE75993PRJNA305921

REPOSITORIES: GEO, ArrayExpress, ENA

Similar Datasets

2016-10-25 | E-GEOD-76494 | ArrayExpress
2012-05-15 | E-GEOD-38006 | ArrayExpress
2012-12-01 | E-GEOD-34212 | ArrayExpress
2016-08-01 | E-GEOD-84974 | ArrayExpress
2012-01-01 | E-GEOD-27240 | ArrayExpress
2014-06-10 | E-GEOD-58305 | ArrayExpress
2013-09-01 | E-GEOD-31944 | ArrayExpress
2015-02-09 | E-GEOD-55735 | ArrayExpress
2015-04-30 | E-GEOD-49805 | ArrayExpress
2012-09-19 | E-GEOD-36398 | ArrayExpress