Transcriptomics

Dataset Information

297

Single cell transcriptome analysis of mouse carotid body glomus cells


ABSTRACT: The carotid body (CB) is a major arterial chemoreceptor containing glomus cells whose activities are regulated by changes in arterial blood contents including oxygen. We employed the single cell RNA­Seq method by performing next-generation sequencing on single glomus cell­derived cDNAs to eliminate contamination of genes derived from other cell types present in the CB. This study has generated a CB expression profile containing novel glomus cell specific genes. The wealth of information provided through this study offers a valuable foundation for identifying molecules functioning in the CB. 8 single CB glomus cells that were confirmed expressing tyrosine hydroxylase (Th), ubiquitin carboxyl-terminal esterase L1 (Uchl1) and potassium channel subfamily K member 3 (Kcnk3) were harvested from P4-5 wild type mice and subjected to single-cell RNA-Seq

ORGANISM(S): Musculus  

SUBMITTER: Hiroaki Matsunami   Ting Zhou  Ming-Shan Chien 

PROVIDER: E-GEOD-76579 | ArrayExpress | 2016-03-15

SECONDARY ACCESSION(S): GSE76579SRP068146PRJNA308083

REPOSITORIES: GEO, ArrayExpress, ENA

Similar Datasets

| GSE99593 | GEO
| PRJNA187012 | ENA
| PRJNA189810 | ENA
| PRJNA431825 | ENA
| PRJNA347589 | ENA
| PRJNA407335 | ENA
| PRJNA174749 | ENA
2005-06-30 | E-MEXP-218 | ArrayExpress
2015-03-31 | E-GEOD-67429 | ArrayExpress
2009-08-01 | E-MTAB-117 | ArrayExpress