Transcriptomics

Dataset Information

3

The signaling pathway involved in wild type and 2D2-gut CD4+ T cell development


ABSTRACT: To find the signalling pathway involved in WT/2D2 CD4+ gut T cell (CD4+ intraepithelial lymphocytes, CD4+IEL) differentiation, particulary to determine whether aryl hydrocarbon receptor (AHR) pathway is involved. Gene expression was analyzed ex vivo in CD4+ T cells that were sorted from Wild type-Gut / 2D2 mouse-Gut / Wild type-Spleen / 2D2 mouse-Spleen (N=3 per group). The genes highly expressed in WT/2D2 Gut compared to WT/2D2 Spleen were selected by k-means clustering. AHR pathway related genes (IPA software) were further selected.

ORGANISM(S): Mus Musculus

TISSUE(S): Spleen, Gut

SUBMITTER: Atsushi Kadowaki   Takashi Yamamura 

PROVIDER: E-GEOD-79748 | ArrayExpress | 2016-04-01

SECONDARY ACCESSION(S): GSE79748PRJNA316926

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-79748.idf.txt Idf
E-GEOD-79748.processed.1.zip Processed
E-GEOD-79748.raw.1.zip Raw
E-GEOD-79748.sdrf.txt Txt
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