Transcriptomics

Dataset Information

1

Effects of SOCS2-AS1 inhibition in prostate cancer cells


ABSTRACT: Prostate cancer is the most common cancer in men and AR downstream signalings promote prostate cancer cell proliferation. We identified a novel androgen-regulated long non-coding (lnc) RNA, SOCS2-AS1. In order to investigate the SOCS2-AS1 function in prostate cancer cells, we performed gene expression in AR-positive prostate cancer cell lines (LNCaP and LTAD) after siSOCS2-AS1 or siSOCS2 treatment. We also treated cells with vehicle or androgen to analyzed the effects of siSOCS2-AS1 on AR function. Observation of androgen dependent gene expression changes after treatmet with siSOCS2-AS1 with microarray.

ORGANISM(S): Homo sapiens  

SUBMITTER: K Takayama   S Inoue  A Misawa  Ken-ichi Takayama 

PROVIDER: E-GEOD-82224 | ArrayExpress | 2016-08-01

SECONDARY ACCESSION(S): GSE82224PRJNA324392

REPOSITORIES: GEO, ArrayExpress

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