Genomics

Dataset Information

271

GATA-2 occupancy in Kasumi-3 cell line


ABSTRACT: GATA-2 is a master regulator of hematopoiesis which controls expression of multiple genes and is implicated in acute myeloid leukemia (AML). However, the molecular mechanism how GATA-2 deregulation causes leukemogenesis is still unclear. In this study, GATA-2 ChIP-squ analysis was conducted in Kasumi-3 AML cell line to identify GATA-2 target genes which play important roles in the pathogenesis of AML. ChIP with GATA-2 antibody was conducted in Kasumi-3 AML cell line and ChIP-seq profile was generated by deep sequencing.

ORGANISM(S): Homo sapiens  

SUBMITTER: Peggy J Farnham   Emery H Bresnick  Koichi Katsumura  Kyle Hewitt 

PROVIDER: E-GEOD-84782 | ArrayExpress | 2016-08-05

SECONDARY ACCESSION(S): GSE84782SRP079678PRJNA331135

REPOSITORIES: GEO, ArrayExpress, ENA

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