Dataset Information


Transcription profiling of Xenopus hybrid femalesex reversal experiment

ABSTRACT: Gene expression was examined in genetic males that were sex-reversed to be phenotypically female compared to normal hybrid females; We used microarrays to test expression in the gonad of sex-reversed females (ZZ) compared to normal females (ZW) Experiment Overall Design: RNA from the ovary of sexually mature individuals was extracted and hybridized onto Affymetrix microarrays.

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Xenopus laevis x Xenopus muelleri  

SUBMITTER: John Malone  

PROVIDER: E-GEOD-9504 | ArrayExpress | 2008-06-16



altmetric image


Physiological sex predicts hybrid sterility regardless of genotype.

Malone John H JH   Michalak P P  

Science (New York, N.Y.) 20080101 5859

Reproductive isolation between biological species is characterized by Haldane's rule, which states that the heterogametic sex (XY or ZW) suffers the most dysfunctional effects of hybridization. It has been hypothesized that, in addition to X-linked recessive genes, Haldane's rule also reflects the faster evolution of genes related to male reproduction (faster-male evolution). We used sex-reversed hybrid Xenopus to test faster-male evolution by examining the fertility of sex-reversed individuals  ...[more]

Similar Datasets

2008-06-16 | E-GEOD-9505 | ArrayExpress
2008-06-16 | E-GEOD-9507 | ArrayExpress
2007-11-07 | GSE9504 | GEO
2007-11-07 | GSE9505 | GEO
| PRJNA99191 | ENA
2019-01-16 | E-MTAB-7188 | ArrayExpress
2018-12-03 | PXD009363 | Pride
2018-01-08 | PXD006352 | Pride
2010-07-24 | GSE23094 | GEO
2013-11-27 | E-GEOD-52218 | ArrayExpress