Transcriptomics

Dataset Information

56

Transcription profiling of human muscle biopises after standard diet and activity regimes


ABSTRACT: Muscle biopsies taken from vastus lateralis muscle of 15 men and 15 women after 3 days of standardized diet and activity to examine effects of sex and age; Subjects were either young adults (7 men and 7 women, 20-29 yr old) or older (8 men and 8 women, 65-75 yr old); Affymetrix U133A and U133B arrays were scanned both before (S1) and after (S2) antibody enhancement. This file has U133A S1 data. Effects of age were computed for men and women separately with an alternative method previously and data submitted as GSE362 (men) and GSE674 (women). Experiment Overall Design: Gene expressions profiles were generated for each individual for a total of 30 profiles (15 male, 15 female, 14 younger, 16 older)

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Homo sapiens  

SUBMITTER: Stephen Welle   

PROVIDER: E-GEOD-9676 | ArrayExpress | 2012-03-27

SECONDARY ACCESSION(S): GSE9676PRJNA103565

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications

Sex-related differences in gene expression in human skeletal muscle.

Welle Stephen S   Tawil Rabi R   Thornton Charles A CA  

PloS one 20080102 1


There is sexual dimorphism of skeletal muscle, the most obvious feature being the larger muscle mass of men. The molecular basis for this difference has not been clearly defined. To identify genes that might contribute to the relatively greater muscularity of men, we compared skeletal muscle gene expression profiles of 15 normal men and 15 normal women by using comprehensive oligonucleotide microarrays. Although there were sex-related differences in expression of several hundred genes, very few  ...[more]

Similar Datasets

2007-11-24 | GSE9676 | GEO
2003-09-22 | GSE674 | GEO
2014-06-02 | E-GEOD-38718 | ArrayExpress
2011-10-12 | E-GEOD-10760 | ArrayExpress
2002-02-01 | GSE17 | GEO
2015-10-06 | E-GEOD-9103 | ArrayExpress
2007-11-01 | GSE9103 | GEO
2015-10-22 | E-GEOD-9103 | ExpressionAtlas
2007-07-16 | GSE8479 | GEO
2012-03-27 | E-GEOD-362 | ArrayExpress