Dataset Information


Transcription profiling of Salmonella enterica serovar Typhimurium hha ydgT mutants

ABSTRACT: transcriptomic analysis of hha ydgT mutants in Salmonella enterica serovar Typhimurium

INSTRUMENT(S): GenePix 4000B [Axon Instruments]

ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium  

SUBMITTER: Cristina Madrid  

PROVIDER: E-MEXP-1303 | ArrayExpress | 2008-01-01


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Modulation of horizontally acquired genes by the Hha-YdgT proteins in Salmonella enterica serovar Typhimurium.

Vivero Aitziber A   Baños Rosa C RC   Mariscotti Javier F JF   Oliveros Juan Carlos JC   García-del Portillo Francisco F   Juárez Antonio A   Madrid Cristina C  

Journal of bacteriology 20071126 3

We describe a transcriptomic study of the effect of hha and ydgT mutations in Salmonella enterica serovar Typhimurium. A large number of genes showing altered expression are located in AT-rich horizontally acquired DNA sequences. Many of these genes have also been reported to be targets for H-NS. As Hha and YdgT interact with H-NS, our findings strongly suggest that Hha and/or YdgT must form complexes with H-NS when they silence these DNA regions. ...[more]

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