Dataset Information


Transcription profiling of mouse postnatal neuroblasts from posterior and anterior rostral migratory streams

ABSTRACT: Postnatal neuroblasts were microdissected by laser micro dissection from posterior and anterior rostral migratory stream (RMS). Neuroblasts in the posterior RMS are just started their migration. Neuroblasts in the anterior RMS are already migrated for several days in the stream


INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Mus musculus  

SUBMITTER: Konstantin Khodosevich  

PROVIDER: E-MEXP-1430 | ArrayExpress | 2008-09-01


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Major signaling pathways in migrating neuroblasts.

Khodosevich Konstantin K   Seeburg Peter H PH   Monyer Hannah H  

Frontiers in Molecular Neuroscience 20090724

Neuronal migration is a key process in the developing and adult brain. Numerous factors act on intracellular cascades of migrating neurons and regulate the final position of neurons. One robust migration route persists postnatally - the rostral migratory stream (RMS). To identify genes that govern neuronal migration in this unique structure, we isolated RMS neuroblasts by making use of transgenic mice that express EGFP in this cell population and performed microarray analysis on RNA. We compared  ...[more]

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