Dataset Information


Transcription profiling of fission yeast treated with hydrogen peroxide in fission yeast wild type and csx1 mutant cells

ABSTRACT: Time course experiments of hydrogen peroxide treated cells for both S. pombe wild type and csx1 mutant cells.

ORGANISM(S): Schizosaccharomyces pombe  

SUBMITTER: Miguel A Rodríguez-Gabriel  Jürg Bähler  John R Yates 3rd  Paul Russell  Gavin Burns  Hayes McDonald  Victoria Martin 

PROVIDER: E-MEXP-176 | ArrayExpress | 2004-10-01


Dataset's files

Action DRS
E-MEXP-176.README.txt Txt
E-MEXP-176.idf.txt Idf Processed Raw
E-MEXP-176.sdrf.txt Txt
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RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress.

Rodríguez-Gabriel Miguel A MA   Burns Gavin G   McDonald W Hayes WH   Martín Victoria V   Yates John R JR   Bähler Jürg J   Russell Paul P  

The EMBO journal 20031201 23

Fission yeast Spc1 (Sty1), a stress-activated mitogen-activated protein kinase (MAPK) homologous to human p38, orchestrates global changes in gene expression in response to diverse forms of cytotoxic stress. This control is partly mediated through Atf1, a transcription factor homologous to human ATF2. How Spc1 controls Atf1, and how the cells tailor gene expression patterns to different forms of stress, are unknown. Here we describe Csx1, a novel protein crucial for survival of oxidative but not  ...[more]

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