Transcriptomics

Dataset Information

139

Transcription profiling of Schistosoma lifecycle


ABSTRACT: Transcriptome analysis throughout the lifecycle of the helminth Schistosoma mansoni.

ORGANISM(S): Schistosoma mansoni  

SUBMITTER: Jennifer Fitzpatrick  

PROVIDER: E-MEXP-2094 | ArrayExpress | 2009-12-31

REPOSITORIES: ArrayExpress

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Publications

Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni.

Nowacki Fanny C FC   Swain Martin T MT   Klychnikov Oleg I OI   Niazi Umar U   Ivens Alasdair A   Quintana Juan F JF   Hensbergen Paul J PJ   Hokke Cornelis H CH   Buck Amy H AH   Hoffmann Karl F KF  

Journal of extracellular vesicles 20151005


BACKGROUND:Penetration of skin, migration through tissues and establishment of long-lived intravascular partners require Schistosoma parasites to successfully manipulate definitive host defences. While previous studies of larval schistosomula have postulated a function for excreted/secreted (E/S) products in initiating these host-modulatory events, the role of extracellular vesicles (EVs) has yet to be considered. Here, using preparatory ultracentrifugation as well as methodologies to globally a  ...[more]

Publication: 1/3

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