Ontology highlight
ABSTRACT:
INSTRUMENT(S): 418 [Affymetrix]
ORGANISM(S): Mus Musculus
SUBMITTER: Barbara Schraml
PROVIDER: E-MEXP-2153 | ArrayExpress | 2009-06-06
REPOSITORIES: ArrayExpress
Action | DRS | |||
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E-MEXP-2153.README.txt | Txt | |||
E-MEXP-2153.eSet.r | Other | |||
E-MEXP-2153.idf.txt | Idf | |||
E-MEXP-2153.idf.txt_original | Idf | |||
E-MEXP-2153.processed.1.zip | Processed |
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Schraml Barbara U BU Hildner Kai K Ise Wataru W Lee Wan-Ling WL Smith Whitney A-E WA Solomon Ben B Sahota Gurmukh G Sim Julia J Mukasa Ryuta R Cemerski Saso S Hatton Robin D RD Stormo Gary D GD Weaver Casey T CT Russell John H JH Murphy Theresa L TL Murphy Kenneth M KM
Nature 20090705 7253
Activator protein 1 (AP-1, also known as JUN) transcription factors are dimers of JUN, FOS, MAF and activating transcription factor (ATF) family proteins characterized by basic region and leucine zipper domains. Many AP-1 proteins contain defined transcriptional activation domains, but BATF and the closely related BATF3 (refs 2, 3) contain only a basic region and leucine zipper, and are considered to be inhibitors of AP-1 activity. Here we show that Batf is required for the differentiation of IL ...[more]