Transcriptomics

Dataset Information

63

MicroRNA profiling of mouse white adipose tissue, brown adipose tissue and skeletal muscle


ABSTRACT: Compare miRNA expression profiles in epididymal white adipose tissue (WAT), interscapular brown adipose tissue (BAT) and skeletal muscle from wild-type C57BL/6J mice

ORGANISM(S): Mus musculus  

SUBMITTER: Huangming Xie  

PROVIDER: E-MEXP-2553 | ArrayExpress | 2010-12-01

REPOSITORIES: ArrayExpress

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Publications


Mammals have two principal types of fat. White adipose tissue primarily serves to store extra energy as triglycerides, whereas brown adipose tissue is specialized to burn lipids for heat generation and energy expenditure as a defence against cold and obesity. Recent studies have demonstrated that brown adipocytes arise in vivo from a Myf5-positive, myoblastic progenitor by the action of Prdm16 (PR domain containing 16). Here, we identified a brown-fat-enriched miRNA cluster, MiR-193b-365, as a k  ...[more]

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