Transcriptomics

Dataset Information

23

Transcription profiling of human cells line with different D10 values to assay radiosensitivity


ABSTRACT: Expression analysis between cell lines that show different "D10" which is one of the parameters for radiosensitivity. This experiment includes three experimental factors: cell line, irradiation dose and time after irradiation.

ORGANISM(S): Homo sapiens  

DISEASE(S): Adenocarcinoma,Glioma,Medulloblastoma,Amelanotic Melanoma,Glioblastoma,Gliosarcoma,Normal,Astrocytoma

SUBMITTER: Atsuko Ishikawa  

PROVIDER: E-MEXP-272 | ArrayExpress | 2006-01-06

REPOSITORIES: ArrayExpress

altmetric image

Publications

Gene expression profile changes correlating with radioresistance in human cell lines.

Ishikawa Ken-ichi K   Koyama-Saegusa Kumiko K   Otsuka Yoshimi Y   Ishikawa Atsuko A   Kawai Seiko S   Yasuda Kaori K   Suga Tomo T   Michikawa Yuichi Y   Suzuki Masao M   Iwakawa Mayumi M   Imai Takashi T  

International journal of radiation oncology, biology, physics 20060501 1


PURPOSE: To identify gene expression profiles specific to radioresistance of human cells. METHODS AND MATERIALS: Global gene expression profiles of a total of 15 tumor and normal fibroblast cell lines were analyzed using DNA microarrays and statistical clustering methods. Initially, six of the cell lines were categorized into radioresistant (RG) or nonradioresistant (NRG) groups according to the radiation dose required to reduce their survival to 10% (D10). Genes for which expression was specifi  ...[more]

Similar Datasets

2006-01-16 | E-MEXP-273 | ArrayExpress
2015-11-12 | E-GEOD-63349 | ArrayExpress
2010-09-27 | E-GEOD-18727 | ArrayExpress
2011-09-13 | E-GEOD-32091 | ArrayExpress
2015-02-01 | E-GEOD-42916 | ArrayExpress
2010-12-03 | E-GEOD-25772 | ArrayExpress
2015-04-01 | E-MTAB-2632 | ArrayExpress
2014-09-18 | E-GEOD-61484 | ArrayExpress
2012-12-30 | E-GEOD-40602 | ArrayExpress
2010-05-26 | E-GEOD-10891 | ArrayExpress