Transcriptomics

Dataset Information

4

ChIP-chip by array of mouse haematopoietic and endothelial cell lines using an anti-H3 trimethyl lysine 4 antibody


ABSTRACT: chromatin immunoprecipitations were performed in mouse haematopoietic and endothelial cell lines using an anti-H3 trimethyl lysine 4 antibody

ORGANISM(S): Mus Musculus

SUBMITTER: Aileen M Smith  

PROVIDER: E-MEXP-2908 | ArrayExpress | 2012-02-01

REPOSITORIES: ArrayExpress

Dataset's files

Source:
Action DRS
E-MEXP-2908.README.txt Txt
E-MEXP-2908.eSet.r Other
E-MEXP-2908.idf.txt Idf
E-MEXP-2908.idf.txt_original Idf
E-MEXP-2908.processed.1.zip Processed
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Publications

Integration of Elf-4 into stem/progenitor and erythroid regulatory networks through locus-wide chromatin studies coupled with in vivo functional validation.

Smith Aileen M AM   Calero-Nieto Fernando J FJ   Schütte Judith J   Kinston Sarah S   Timms Richard T RT   Wilson Nicola K NK   Hannah Rebecca L RL   Landry Josette-Renee JR   Göttgens Berthold B  

Molecular and cellular biology 20111212 4


The ETS transcription factor Elf-4 is an important regulator of hematopoietic stem cell (HSC) and T cell homeostasis. To gain insights into the transcriptional circuitry within which Elf-4 operates, we used comparative sequence analysis coupled with chromatin immunoprecipitation (ChIP) with microarray technology (ChIP-chip) assays for specific chromatin marks to identify three promoters and two enhancers active in hematopoietic and endothelial cell lines. Comprehensive functional validation of e  ...[more]

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