Ontology highlight
ABSTRACT:
INSTRUMENT(S): 418 [Affymetrix]
SUBMITTER: Juan Liao
PROVIDER: E-MEXP-2995 | ArrayExpress | 2011-03-01
REPOSITORIES: ArrayExpress
Action | DRS | |||
---|---|---|---|---|
E-MEXP-2995.README.txt | Txt | |||
E-MEXP-2995.eSet.r | Other | |||
E-MEXP-2995.idf.txt | Idf | |||
E-MEXP-2995.processed.1.zip | Processed | |||
E-MEXP-2995.raw.1.zip | Raw |
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Molecular cancer research : MCR 20110204 3
Batf is a basic leucine zipper transcription factor belonging to the activator protein-1 superfamily. Batf expression is regulated following stimulation of both lymphoid and myeloid cells. When treated with leukemia inhibitory factor, mouse M1 myeloid leukemia cells commit to a macrophage differentiation program that is dependent on Stat3 and involves the induction of Batf gene transcription via the binding of Stat3 to the Batf promoter. RNA interference was employed to block Batf induction in t ...[more]