Dataset Information


FOXK2 ChIP-chip

ABSTRACT: Chromatin immunoprecipitation of FOXK2 (tagged with Flag and His tags) in U2OS cells detected by Affymetrix human promoter array 1.0R.

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Homo sapiens  


PROVIDER: E-MEXP-3116 | ArrayExpress | 2011-11-03


Dataset's files

Action DRS
E-MEXP-3116.README.txt Txt
E-MEXP-3116.eSet.r Other
E-MEXP-3116.idf.txt Idf Processed Raw
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The forkhead transcription factor FOXK2 promotes AP-1-mediated transcriptional regulation.

Ji Zongling Z   Donaldson Ian J IJ   Liu Jingru J   Hayes Andrew A   Zeef Leo A H LA   Sharrocks Andrew D AD  

Molecular and cellular biology 20111114 2

The transcriptional control circuitry in eukaryotic cells is complex and is orchestrated by combinatorially acting transcription factors. Forkhead transcription factors often function in concert with heterotypic transcription factors to specify distinct transcriptional programs. Here, we demonstrate that FOXK2 participates in combinatorial transcriptional control with the AP-1 transcription factor. FOXK2 binding regions are widespread throughout the genome and are often coassociated with AP-1 bi  ...[more]

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