Dataset Information


Transcription profiling of FCR3 P. falciparum parasites phenotypicaly selected for adhesion on CSA or CD36

ABSTRACT: Comparison of FCR3 P. falciparum parasites phenotypicaly selected for adhesion on CSA or CD36.

INSTRUMENT(S): Scanning hardware


PROVIDER: E-MEXP-319 | ArrayExpress | 2005-12-31


Dataset's files

Action DRS
E-MEXP-319.README.txt Txt
E-MEXP-319.idf.txt Idf Processed Raw
E-MEXP-319.sdrf.txt Txt
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Transcriptome analysis of antigenic variation in Plasmodium falciparum--var silencing is not dependent on antisense RNA.

Ralph Stuart A SA   Bischoff Emmanuel E   Mattei Denise D   Sismeiro Odile O   Dillies Marie-Agnès MA   Guigon Ghislaine G   Coppee Jean-Yves JY   David Peter H PH   Scherf Artur A  

Genome biology 20051031 11

<h4>Background</h4>Plasmodium falciparum, the causative agent of the most severe form of malaria, undergoes antigenic variation through successive presentation of a family of antigens on the surface of parasitized erythrocytes. These antigens, known as Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) proteins, are subject to a mutually exclusive expression system, and are encoded by the multigene var family. The mechanism whereby inactive var genes are silenced is poorly understood.  ...[more]

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