Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): Kashin-beck Disease,Normal
SUBMITTER: Feng Zhang
PROVIDER: E-MEXP-3196 | ArrayExpress | 2011-10-01
REPOSITORIES: ArrayExpress
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E-MEXP-3196.README.txt | Txt | |||
E-MEXP-3196.eSet.r | Other | |||
E-MEXP-3196.idf.txt | Idf | |||
E-MEXP-3196.processed.1.zip | Processed | |||
E-MEXP-3196.raw.1.zip | Raw |
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PloS one 20110729 7
Kashin-Beck Disease (KBD) is an endemic osteochondropathy, the pathogenesis of which remains unclear now. In this study, we compared gene expression profiles of articular cartilage derived respectively from KBD patients and normal controls. Total RNA were isolated, amplified, labeled and hybridized to Agilent human 1A 22 k whole genome microarray chip. qRT-PCR was conducted to validate our microarray data. We detected 57 up-regulated genes (ratios ≥2.0) and 24 down-regulated genes (ratios ≤0.5) ...[more]