Dataset Information


Sampaio_UMinho_Candida albicans Mutant vs Wt_YPD

ABSTRACT: Candida albicans strain with RLM1 deletion was compared to wild type strain. Growth in YPD medium. Two comparisons were performed on microarray in dye-swap hybridizations.

ORGANISM(S): Candida albicans  

SUBMITTER: Laura Carreto  

PROVIDER: E-MEXP-3247 | ArrayExpress | 2012-01-01


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Candida albicans cell wall is important for growth and interaction with the environment. RLM1 is one of the putative transcription factors involved in the cell wall integrity pathway, which plays an important role in the maintenance of the cell wall integrity. In this work we investigated the involvement of RLM1 in the cell wall biogenesis and in virulence. Newly constructed C. albicans Δ/Δrlm1 mutants showed typical cell wall weakening phenotypes, such as hypersensitivity to Congo Red, Calcoflu  ...[more]

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