Ontology highlight
ABSTRACT:
INSTRUMENT(S): Axon GenePix 4000B scanning hardware
ORGANISM(S): Schizosaccharomyces pombe
SUBMITTER: Juan Mata Chris J Penkett Jacky Hayles Pietro Lio Gabriella Rustici Katja Kivinen Gavin Burns Paul Nurse Alvis Brazma Jurg Bahler
PROVIDER: E-MEXP-61 | ArrayExpress | 2004-04-01
REPOSITORIES: ArrayExpress
Nature genetics 20040613 8
Cell-cycle control of transcription seems to be universal, but little is known about its global conservation and biological significance. We report on the genome-wide transcriptional program of the Schizosaccharomyces pombe cell cycle, identifying 407 periodically expressed genes of which 136 show high-amplitude changes. These genes cluster in four major waves of expression. The forkhead protein Sep1p regulates mitotic genes in the first cluster, including Ace2p, which activates transcription in ...[more]