Transcriptomics

Dataset Information

238

Gene Expression Profile Analysis of T1 and T2 Breast Cancer Tumors


ABSTRACT: The purpose of this study is to search for molecular signatures characterizing clinical T1 and T2 tumors and to better identify patients of high risk of relapse and/or metastasis. In total 46 samples, 29 T1 and 17 T2 infiltrating ductal carcinomas, were included.

SUBMITTER: Margit Riis   Torben Lüders  

PROVIDER: E-MTAB-1049 | ArrayExpress | 2013-01-17

REPOSITORIES: ArrayExpress

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Publications

Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways.

Riis Margit L H ML   Zhao Xi X   Kaveh Fateme F   Vollan Hilde S HS   Nesbakken Anne-Jorunn AJ   Solvang Hiroko K HK   Lüders Torben T   Bukholm Ida R K IR   Kristensen Vessela N VN  

ISRN oncology 20130228


Breast cancers today are of predominantly T1 (0.1 ≥ 2.0 cm) or T2 (>2 ≤ 5 cm) categories due to early diagnosis. Molecular profiling using microarrays has led to the notion of breast cancer as a heterogeneous disease both clinically and molecularly. Given the prognostic power and clinical use of tumor size, the purpose of this study was to search for molecular signatures characterizing clinical T1 and T2. In total 46 samples were included in the discovery dataset. After adjusting for hormone rec  ...[more]

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