Proteomics

Dataset Information

0

Linear epitope-specific IgG responses to SARS-CoV-2 and related human coronaviruses in human COVID-19 convalescent sera


ABSTRACT: The on-going COVID-19 pandemic requires a deeper understanding of the long-term antibody responses that persist following SARS-CoV-2 infection. To that end, we determined epitope-specific IgG antibody responses in COVID-19 convalescent sera collected at 5 months post-diagnosis and compared that to sera from naïve individuals. Each serum sample was reacted with a high-density peptide microarray representing the complete proteome of SARS-CoV-2 as 15 mer peptides with 11 amino acid overlap and homologs of spike glycoprotein, nucleoprotein, membrane protein, and envelope small membrane protein from related human coronaviruses. Binding signatures were compared between COVID-19 convalescent patients and naïve individuals using the web service tool EPIphany.

ORGANISM(S): Homo sapiens  

DISEASE(S): Covid-19,None

SUBMITTER: Antonio Facciuolo   Scott Napper  

PROVIDER: E-MTAB-10740 | ArrayExpress | 2022-02-05

REPOSITORIES: ArrayExpress

Dataset's files

Source:
Action DRS
E-MTAB-10740.idf.txt Idf
E-MTAB-10740.raw.1.zip Raw
E-MTAB-10740.sdrf.txt Txt
Items per page:
1 - 3 of 3

Similar Datasets

2020-01-01 | S-EPMC7534331 | BioStudies
2021-01-01 | S-EPMC7936871 | BioStudies
2020-01-01 | S-EPMC7665673 | BioStudies
2021-03-20 | E-MTAB-10169 | ArrayExpress
2020-01-01 | S-EPMC7594855 | BioStudies
2020-01-01 | S-EPMC7482996 | BioStudies
2021-10-07 | GSE184806 | GEO
2020-01-01 | S-EPMC7448895 | BioStudies
2020-01-01 | S-EPMC7568577 | BioStudies
2020-01-01 | S-EPMC7217240 | BioStudies