Dataset Information


Linear epitope-specific IgG responses to SARS-CoV-2 and related human coronaviruses in human COVID-19 convalescent sera

ABSTRACT: The on-going COVID-19 pandemic requires a deeper understanding of the long-term antibody responses that persist following SARS-CoV-2 infection. To that end, we determined epitope-specific IgG antibody responses in COVID-19 convalescent sera collected at 5 months post-diagnosis and compared that to sera from naïve individuals. Each serum sample was reacted with a high-density peptide microarray representing the complete proteome of SARS-CoV-2 as 15 mer peptides with 11 amino acid overlap and homologs of spike glycoprotein, nucleoprotein, membrane protein, and envelope small membrane protein from related human coronaviruses. Binding signatures were compared between COVID-19 convalescent patients and naïve individuals using the web service tool EPIphany.

ORGANISM(S): Homo sapiens  

DISEASE(S): Covid-19,None

SUBMITTER: Antonio Facciuolo   Scott Napper  

PROVIDER: E-MTAB-10740 | ArrayExpress | 2022-02-05


Dataset's files

Action DRS
E-MTAB-10740.idf.txt Idf Raw
E-MTAB-10740.sdrf.txt Txt
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