Transcriptomics

Dataset Information

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Axon Guidance Receptor ROBO3 Modulates Subtype Identity and Prognosis via AXL-associated Inflammatory Network in Pancreatic Cancer


ABSTRACT: Recently, genome-wide molecular analyses have identified an altered axon guidance SLIT-ROBO signaling pathway in Pancreatic ductal adenocarcinoma (PDAC). To examine whether ROBO3 signaling is involved in the transcriptional determination of basal-like PDAC-subtype specification and functions, we performed RNA-seq analysis following ROBO3 silencing in the basal-like cell line PANC1.

INSTRUMENT(S): Illumina HiSeq 4000

DISEASE(S): Pancreatic Ductal Adenocarcinoma

SUBMITTER: Florian Wegwitz  

PROVIDER: E-MTAB-11476 | ArrayExpress | 2022-07-31

SECONDARY ACCESSION(S): ERP135745

REPOSITORIES: ArrayExpress, ENA

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