Genomics,Multiomics

Dataset Information

4

ChIP-seq of M. smegmatis wild type and glnR deletion strains to investigate growth in nitrogen limiting conditions


ABSTRACT: M. smegmatis wild type and glnR deletion strains grown in nitrogen limiting conditions (1 mM ammonium sulphate nitrogen source). Samples taken 1 hour after nitrogen depletion from the media for each strain.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Mycolicibacterium smegmatis  

SUBMITTER: Geraint Barton  

PROVIDER: E-MTAB-1456 | ArrayExpress | 2013-06-12

SECONDARY ACCESSION(S): ERP002151

REPOSITORIES: ArrayExpress, ENA

Dataset's files

Source:
Action DRS
E-MTAB-1456.idf.txt Idf
E-MTAB-1456.sdrf.txt Txt
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Publications

Genome wide analysis of the complete GlnR nitrogen-response regulon in Mycobacterium smegmatis.

Jenkins Victoria A VA   Barton Geraint R GR   Robertson Brian D BD   Williams Kerstin J KJ  

BMC genomics 20130504


<h4>Background</h4>Nitrogen is an essential element for bacterial growth and an important component of biological macromolecules. Consequently, responding to nitrogen limitation is critical for bacterial survival and involves the interplay of signalling pathways and transcriptional regulation of nitrogen assimilation and scavenging genes. In the soil dwelling saprophyte Mycobacterium smegmatis the OmpR-type response regulator GlnR is thought to mediate the transcriptomic response to nitrogen lim  ...[more]

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