Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Yuichi Abe
PROVIDER: E-MTAB-1491 | ArrayExpress | 2013-12-10
REPOSITORIES: ArrayExpress
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E-MTAB-1491.idf.txt | Idf | |||
E-MTAB-1491.processed.1.zip | Processed | |||
E-MTAB-1491.processed.2.zip | Processed | |||
E-MTAB-1491.raw.1.zip | Raw | |||
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Gastroenterology 20130516 3
<h4>Background & aims</h4>A 3-dimensional (3D) culture system for immortalized human hepatocytes (HuS-E/2 cells) recently was shown to support the lifecycle of blood-borne hepatitis C virus (HCV). We used this system to identify proteins that are active during the HCV lifecycle under 3D culture conditions.<h4>Methods</h4>We compared gene expression profiles of HuS-E/2 cells cultured under 2-dimensional and 3D conditions. We identified signaling pathways that were activated differentially in the ...[more]