Transcriptomics

Dataset Information

238

Transcription profiling by array of xenografted tumors derived from human ovarian cell line model A2780 and its cisplatin resistant variant A2780cis


ABSTRACT: Molecular mechanisms underlying the development of resistance to platinum treatment in patients with ovarian cancer remain poorly understood. This is mainly due to the lack of appropriate in vivo models allowing identification of factors that are regulated during initial treatment and of acquired resistance-related genes. In this study, we used whole genome microarrays and linear model analysis to identify potential resistance-related genes by comparing the expression profiles of the parental human ovarian cancer model A2780 and its cisplatin-resistant variant A2780cis, before and after carboplatin treatment in vivo.

ORGANISM(S): Homo sapiens  

SUBMITTER: Julia C. Meier  

PROVIDER: E-MTAB-1858 | ArrayExpress | 2013-10-01

REPOSITORIES: ArrayExpress

Similar Datasets

2014-12-01 | E-MTAB-1841 | ArrayExpress
2014-05-01 | E-MTAB-1882 | ArrayExpress
2013-07-22 | E-GEOD-39337 | ArrayExpress
2015-06-17 | E-GEOD-58586 | ArrayExpress
2016-05-17 | E-GEOD-77731 | ArrayExpress
2016-05-17 | E-GEOD-77728 | ArrayExpress
2007-07-30 | E-TABM-53 | ArrayExpress
2018-07-29 | E-MTAB-5644 | ArrayExpress
2009-09-15 | E-GEOD-14829 | ArrayExpress
2008-11-01 | E-MEXP-1673 | ArrayExpress