Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: EGAC00001000064EGAD00010000554EGAS00001000647EGAO00000000078EGAO00000000086EGAD00010000556
ORGANISM(S): Homo sapiens
DISEASE(S): Lung Cancer
SUBMITTER: Martin Peifer
PROVIDER: E-MTAB-1999 | ArrayExpress | 2013-10-17
REPOSITORIES: ArrayExpress
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E-MTAB-1999.idf.txt | Idf | |||
E-MTAB-1999.raw.1.zip | Raw | |||
E-MTAB-1999.sdrf.txt | Txt |
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Science translational medicine 20131001 209
We characterized genome alterations in 1255 clinically annotated lung tumors of all histological subgroups to identify genetically defined and clinically relevant subtypes. More than 55% of all cases had at least one oncogenic genome alteration potentially amenable to specific therapeutic intervention, including several personalized treatment approaches that are already in clinical evaluation. Marked differences in the pattern of genomic alterations existed between and within histological subtyp ...[more]