Transcriptomics

Dataset Information

313

Identification of LincRNA signtures in human primary lymphocyte subsets


ABSTRACT: Identification of LincRNA signtures in human primary lymphocyte subsets

INSTRUMENT(S): Illumina HiScanSQ

ORGANISM(S): Homo sapiens  

SUBMITTER: Raoul JP Bonnal   Massimiliano Pagani  

PROVIDER: E-MTAB-2319 | ArrayExpress | 2015-01-25

SECONDARY ACCESSION(S): ERP004883

REPOSITORIES: ArrayExpress, ENA

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Publications


Long noncoding RNAs are emerging as important regulators of cellular functions, but little is known of their role in the human immune system. Here we investigated long intergenic noncoding RNAs (lincRNAs) in 13 subsets of T lymphocytes and B lymphocytes by next-generation sequencing-based RNA sequencing (RNA-seq analysis) and de novo transcriptome reconstruction. We identified over 500 previously unknown lincRNAs and described lincRNA signatures. Expression of linc-MAF-4, a chromatin-associated  ...[more]

Publication: 1/2

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