Dataset Information


Chlamydomonas reinhardtii transcriptional responses to cerium dioxide nanoparticles

ABSTRACT: Agilent gene expression microarrays (Bham Chlamydomonas reinhardtii Agilent-029192 15k v1) were used to profile transcriptional changes afeter exposure of Chlamydomonas reinardtii algae to cerium dioxide nanoparticles.

ORGANISM(S): Chlamydomonas reinhardtii  

SUBMITTER: Tim D Williams  

PROVIDER: E-MTAB-2454 | ArrayExpress | 2014-09-01


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Molecular toxicity of cerium oxide nanoparticles to the freshwater alga Chlamydomonas reinhardtii is associated with supra-environmental exposure concentrations.

Taylor Nadine S NS   Merrifield Ruth R   Williams Tim D TD   Chipman J Kevin JK   Lead Jamie R JR   Viant Mark R MR  

Nanotoxicology 20150305 1

Ceria nanoparticles (NPs) are widely used as fuel catalysts and consequently are likely to enter the environment. Their potential impacts on. biota at environmentally relevant concentrations, including uptake and toxicity, remain to be elucidated and quantitative data on which to assess risk are sparse. Therefore, a definitive assessment of the molecular and phenotypic effects of ceria NPs was undertaken, using well-characterised mono-dispersed NPs as their toxicity is likely to be higher, enabl  ...[more]

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