Transcriptomics

Dataset Information

46

Transcription profiling by array of rats caudal vestibular nucleus (CVN) after rotation to study motion sickness susceptibility


ABSTRACT: Motion sickness susceptible (MSS) and insusceptible (inMSS) rats were identified by quantifying rotation-induced MS symptoms: defecation and spontaneous locomotion activity. Microarray analysis was used to screen differentially expressed genes in the caudal vestibular nucleus (CVN) after rotation.

ORGANISM(S): Rattus norvegicus  

SUBMITTER: Yi-ling Cai  

PROVIDER: E-MTAB-3213 | ArrayExpress | 2015-01-08

REPOSITORIES: ArrayExpress

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Publications

Differential Gene Expression Profile in the Rat Caudal Vestibular Nucleus is Associated with Individual Differences in Motion Sickness Susceptibility.

Wang Jun-Qin JQ   Qi Rui-Rui RR   Zhou Wei W   Tang Yi-Fan YF   Pan Lei-Lei LL   Cai Yi-Ling YL  

PloS one 20150424 4


To identify differentially expressed genes associated with motion sickness (MS) susceptibility in the rat caudal vestibular nucleus.We identified MS susceptible (MSS) and insusceptible (inMSS) rats by quantifying rotation-induced MS symptoms: defecation and spontaneous locomotion activity. Microarray analysis was used to screen differentially expressed genes in the caudal vestibular nucleus (CVN) after rotation. Plasma stress hormones were identified by radioimmunoassay. Candidate genes were sel  ...[more]

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