Transcriptomics

Dataset Information

5

Transcriptional profiling by array of U2OS cells with activated transcription factor FOXO3


ABSTRACT: Transcription factors belonging to the same transcription factor families contain very similar DNA binding domains and hence have the potential to bind to related DNA sequences. However subtle differences in binding specificities can be detected in vitro with the potential to direct specific responses in vivo. In this study the binding properties of three Forkhead transcription factors, FOXK2, FOXO3 and FOXJ3 were studied in vivo. Here we submit the gene expression component of this study. LY294002 treatment of U2OS cells which promotes FOXO3 translocation to the nucleus, and hence activation of the FOXO3 target genes.

ORGANISM(S): Homo sapiens  

SUBMITTER: Leo Zeef  

PROVIDER: E-MTAB-3763 | ArrayExpress | 2016-01-20

REPOSITORIES: ArrayExpress

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