Transcriptomics

Dataset Information

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The transcriptome of Japanese quail Neuroretinas cell line (QNR/D)


ABSTRACT: Our research focus is to study the genetic etiology and molecular mechanisms of glaucoma, a disease characterized by death of the retinal ganglion cell. The QNR/D cells, the only well validated retinal ganglion cell line, are derived from the neuroretina of quail (Coturnix coturnix japonica) embryos at 7 days gestation, and contain RGC (80%) and amacrine cell (20%) populations. With the aim of investigating the effect of candidate gene on glaucoma, the QNR/D cells were transfected in four different conditions. The RNA-Sequencing analysis on these transfected cell lines to identify the related proteins with differential expression profiles.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Coturnix japonica  

SUBMITTER: Chen-Hsin Yu  

PROVIDER: E-MTAB-3832 | ArrayExpress | 2016-03-01

SECONDARY ACCESSION(S): ERP011662

REPOSITORIES: ArrayExpress, ENA

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