Transcriptomics

Dataset Information

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Transcription profiling of mouse brain endothelial cells in host mice carrying xenografts of patient-derived glioblastomas with distinct histological phenotypes


ABSTRACT: Here, we analyzed patient-derived glioblastoma xenografts generated in the mouse brain that give rise to three different histological phenotypes: (i) a highly invasive phenotype (ii) a highly angiogenic phenotype and (iii) an intermediate phenotype. Cell type-specific transcriptomic profiles of tumor and stromal endothelial cells were analyzed to reveal phenotype-specific gene expression patterns and the reciprocal crosstalk between tumor and stromal endothelial cells. This part of the study contains the analysis of the stromal endothelial cells of the host mice. The analysis of the patient-derived tumor cells is found under E-MTAB-3948.

ORGANISM(S): Mus Musculus

DISEASE(S): Glioblastoma Multiforme,Normal

SUBMITTER: Tony KAOMA  

PROVIDER: E-MTAB-3949 | ArrayExpress | 2016-06-30

REPOSITORIES: ArrayExpress

Dataset's files

Source:
Action DRS
E-MTAB-3949.idf.txt Idf
E-MTAB-3949.idf.txt_original Idf
E-MTAB-3949.processed.1.zip Processed
E-MTAB-3949.raw.1.zip Raw
E-MTAB-3949.sdrf.txt Txt
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