Ontology highlight
ABSTRACT:
ORGANISM(S): Mycobacterium tuberculosis H37Rv
SUBMITTER: Rose Elizabeth E Jeeves
Steve T Pullan
Joanna Bacon
PROVIDER: E-MTAB-4093 | ArrayExpress | 2016-03-25
REPOSITORIES: ArrayExpress
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E-MTAB-4093.idf.txt | Idf | ||
E-MTAB-4093.raw.1.zip | Raw | ||
E-MTAB-4093.raw.2.zip | Raw | ||
E-MTAB-4093.sdrf.txt | Txt |
BMC infectious diseases 20160517
<h4>Background</h4>Pyrazinamide (PZA) plays an essential part in the shortened six-month tuberculosis (TB) treatment course due to its activity against slow-growing and non-replicating organisms. We tested whether PZA preferentially targets slow growing cells of Mycobacterium tuberculosis that could be representative of bacteria that remain after the initial kill with isoniazid (INH), by observing the response of either slow growing or fast growing bacilli to differing concentrations of PZA.<h4> ...[more]