Transcriptomics

Dataset Information

21

Transcription profiling by array of FOXP3 overexpression in resting and activated mouse CD4+ T cells


ABSTRACT: Foxp3-mediated gene expression program in resting vs. activated CD4+ T cells The microarray part of this work consists of 12 Affymetrix assays corresponding to 3 biological replicates for each of 4 conditions for CD4+CD25- cells. Cells were either transduced with an empty vector or a vector encoding FOXP3, and in each case cells were either stimulated or not by anti-CD3/anti-CD28.

INSTRUMENT(S): Affymetrix GeneChip Scanner 3000 7G

ORGANISM(S): Mus musculus  

SUBMITTER: Andrew D Wells  

PROVIDER: E-MTAB-4561 | ArrayExpress | 2016-09-24

REPOSITORIES: ArrayExpress

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Publications


Plant bZIP group I transcription factors have been reported mainly for their role during vascular development and osmosensory responses. Interestingly, bZIP29 has been identified in a cell cycle interactome, indicating additional functions of bZIP29 in plant development. Here, bZIP29 was functionally characterized to study its role during plant development. It is not present in vascular tissue but is specifically expressed in proliferative tissues. Genome-wide mapping of bZIP29 target genes conf  ...[more]

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