Transcriptomics

Dataset Information

755

RNA sequencing of pancreatic adenocarcinoma (PDAC) xenograft samples


ABSTRACT: Pancreatic adenocarcinoma (PDAC) is one of the most lethal human malignancies and a major health problem. Patient-derived xenografts (PDX) are appearing as a prime approach for preclinical studies despite being insufficiently characterized as a model of the human disease and its diversity. We generated subcutaneous PDX from PDAC samples obtained either surgically or using diagnostic biopsies (endoscopic ultrasound guided fine needle aspirate). The extensive multiomics characterization of the xenografts demonstrated that PDX is a suitable model for preclinical studies, representing the diversity of the primary cancers. this dataset, describe the RNA sequencing data used in the multiomics study.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Homo sapiens  

SUBMITTER: Nabila Elarouici  

PROVIDER: E-MTAB-5039 | ArrayExpress | 2017-12-12

SECONDARY ACCESSION(S): ERP022034

REPOSITORIES: ArrayExpress, ENA

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