Dataset Information


Transcription profiling by array of Trypanosoma brucei in a time course after starvation

ABSTRACT: Tbrucei_Starve_Synch_MA

ORGANISM(S): Trypanosoma brucei  

SUBMITTER: Stuart K Archer  

PROVIDER: E-MTAB-515 | ArrayExpress | 2011-04-01


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The cell cycle regulated transcriptome of Trypanosoma brucei.

Archer Stuart K SK   Inchaustegui Diana D   Queiroz Rafael R   Clayton Christine C  

PloS one 20110331 3

Progression of the eukaryotic cell cycle requires the regulation of hundreds of genes to ensure that they are expressed at the required times. Integral to cell cycle progression in yeast and animal cells are temporally controlled, progressive waves of transcription mediated by cell cycle-regulated transcription factors. However, in the kinetoplastids, a group of early-branching eukaryotes including many important pathogens, transcriptional regulation is almost completely absent, raising question  ...[more]

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