Transcriptomics

Dataset Information

179

MicroRNA profiling for prediction of chemoradiation efficacy in locally advanced head and neck squamous cell carcinoma


ABSTRACT: The predictive value of microRNAs for the efficacy of chemoradiation (CRTX) in locally advanced head and neck squamous cell carcinoma (HNSCC) was evaluated. Formalin-fixed, paraffin-embedded tumor material was collected from patients with locally advanced HNSCC treated within the ARO-0401 phase III trial with radiotherapy in combination with either 5-fluorouracil/cisplatin (CDDP-CRTX) or 5-fluorouracil/mitomycin C (MMC-CRTX).

ORGANISM(S): Homo sapiens  

SUBMITTER: Anne-Katrin Heß  

PROVIDER: E-MTAB-5198 | ArrayExpress | 2017-03-30

REPOSITORIES: ArrayExpress

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Publications

MiR-200b and miR-155 as predictive biomarkers for the efficacy of chemoradiation in locally advanced head and neck squamous cell carcinoma.

Hess Anne-Katrin AK   Müer Annika A   Mairinger Fabian Dominik FD   Weichert Wilko W   Stenzinger Albrecht A   Hummel Michael M   Budach Volker V   Tinhofer Ingeborg I  

European journal of cancer (Oxford, England : 1990) 20170326


The predictive value of microRNAs (miRNAs) in tumour cells and infiltrating immune cells for the efficacy of chemoradiation (CRTX) in locally advanced head and neck squamous cell carcinoma (HNSCC) was evaluated.Formalin-fixed, paraffin-embedded tumour material was collected from patients with locally advanced HNSCC treated within the ARO-0401 phase III trial with radiotherapy in combination with either 5-fluorouracil/cisplatin (CDDP-CRTX) or 5-fluorouracil/mitomycin C (MMC-CRTX). MiRNA and immun  ...[more]

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