Genomics

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ChIP-seq of definitive endoderm cells derived in vitro from human embryonic stem cells in order to study the role of transcription factor GATA6 in human pancreas development


ABSTRACT: Mutant GATA6 hPSCs were obtained by TALEN genome editing or re-programmed from patient fibroblasts. Along with wild-type H9 cells, these GATA6 mutant cell lines were differentiated into SOX17+/CXCR4+ endodermal cells (day 3). The purpose of this work was to study the role of GATA6 in the development of the human pancreas at a molecular level.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Homo sapiens  

SUBMITTER: Ludovic Vallier  Crystal Chia  Ray Dunn       

PROVIDER: E-MTAB-5959 | ArrayExpress | 2019-03-13

SECONDARY ACCESSION(S): ERP024452

REPOSITORIES: ArrayExpress, ENA

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