Transcriptomics

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Comparative gene expression profiling of tobacco-associated HPV-positive versus negative oral squamous carcinoma cell lines


ABSTRACT: HPV-positive oral squamous cell carcinomas (OSCCs) are specific biological and clinical entities, characterized by a more favorable prognosis compared to HPV-negative OSCCs and occurring generally in non-smoking and non-drinking younger individuals. However, poor information is available on the molecular and the clinical behavior of HPV-positive oral cancers occurring in smoking/drinking subjects. Thus, this study was designed to compare, at molecular level, two OSCC cell lines, both derived from drinking and smoking individuals and differing for presence/absence of HPV infection.

ORGANISM(S): Homo sapiens  

SUBMITTER: Vittorio Simeon   Matteo Landriscina  

PROVIDER: E-MTAB-6152 | ArrayExpress | 2019-12-01

REPOSITORIES: ArrayExpress

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