Genomics

Dataset Information

35

The IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation (ChIP-seq)


ABSTRACT: The IRE1a-XBP1 pathway, a conserved adaptive response to the unfolded protein response, is indispensable for development of the secretory cells. It maintains endoplasmic reticulum homeostasis by enhancing protein folding and the secretory capacity of the cells. Here, we used a modified ChIP-seq protocol (ChIPmentation) to investigate the genome-wide binding events of the transcription factor XBP1 in differentiated mouse Th2 cells.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Mus musculus  

SUBMITTER: Xi Chen  

PROVIDER: E-MTAB-6327 | ArrayExpress | 2018-10-06

SECONDARY ACCESSION(S): ERP105843

REPOSITORIES: ArrayExpress, ENA

Similar Datasets

2017-12-14 | E-MTAB-6292 | ArrayExpress
2018-07-06 | E-MTAB-5918 | ArrayExpress
2019-03-20 | E-MTAB-7543 | ArrayExpress
2017-12-06 | E-MTAB-6276 | ArrayExpress
2018-10-10 | E-MTAB-6714 | ArrayExpress
2015-12-08 | E-GEOD-67633 | ArrayExpress
2015-08-01 | E-GEOD-70072 | ArrayExpress
2016-09-01 | E-GEOD-80152 | ArrayExpress
2017-09-18 | E-MTAB-5953 | ArrayExpress
2016-09-01 | E-GEOD-80154 | ArrayExpress