Transcriptomics

Dataset Information

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MRNA-Integrative multi-omics survey of effects carbon-based engineered nanomaterials on lung derived cell-lines


ABSTRACT: In this study we exposed three human lung derived cell lines to sublethal dosages of nanomaterials for a limited amount of time. For the first time, we assessed the simultaneous effects of nanomaterials exposure on three distinct molecular layers along with their interactions in the determination of the MOA of 10 carbon based nanomaterials. By performing an integrative analysis we provide here a complete picture of the interaction between regulatory factors (DNA methylation and miRNAs) and mRNA deregulation subsequent to exposing different cellular systems to different nanomaterials.

ORGANISM(S): Homo sapiens  

DISEASE(S): Carcinoma,Acute Monocytic Leukemia,Normal

SUBMITTER: Greco Dario  

PROVIDER: E-MTAB-6396 | ArrayExpress | 2018-05-19

REPOSITORIES: ArrayExpress

Dataset's files

Source:
Action DRS
E-MTAB-6396.idf.txt Idf
E-MTAB-6396.idf.txt_original Idf
E-MTAB-6396.processed.1.zip Processed
E-MTAB-6396.raw.1.zip Raw
E-MTAB-6396.raw.2.zip Raw
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