Dataset Information


Yeast carbon and nitrogen impulse transient data in chemostat

ABSTRACT: Wild type S. cerevisiae cells were grown under glucose or ammonium limitation in fully controlled aerobic chemostat cultures. At steady state, the limited nutrient was introduced into the growth medium in an impulse like manner to recover the medium to its non-limiting conditions. Samples were collected at steady state and following the impulse (20s, 40s, 60s, 8 min, 16 min, 24 min, 32 min, 1 hr, 2hr, 3hr, 4hr, 5hr, 7 hr) until the effect of the perturbation ceased to exist. The last sample was collected the second time the chemostat reached steady state.

ORGANISM(S): Saccharomyces cerevisiae  

SUBMITTER: Duygu Dikicioglu  

PROVIDER: E-MTAB-643 | ArrayExpress | 2011-10-03


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How yeast re-programmes its transcriptional profile in response to different nutrient impulses.

Dikicioglu Duygu D   Karabekmez Erkan E   Rash Bharat B   Pir Pinar P   Kirdar Betul B   Oliver Stephen G SG  

BMC systems biology 20110925

A microorganism is able to adapt to changes in its physicochemical or nutritional environment and this is crucial for its survival. The yeast, Saccharomyces cerevisiae, has developed mechanisms to respond to such environmental changes in a rapid and effective manner; such responses may demand a widespread re-programming of gene activity. The dynamics of the re-organization of the cellular activities of S. cerevisiae in response to the sudden and transient removal of either carbon or nitrogen lim  ...[more]

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