Monocyte-derived IL-1 and IL-6 are differentially required for cytokine release syndrome and neurotoxicity by CAR-T cells.
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ABSTRACT: Single-cell transcriptome profiling using a 3' droplet-based platform (Chromium,10x Genomics) of human CD45+ leukocytes isolated from leukemic HuSGM3 mice infused with CD19.28z CAR-T cells, two days after cytokine release syndrome (CRS) onset and 5 days later.
INSTRUMENT(S): NextSeq 500
ORGANISM(S): Homo sapiens
SUBMITTER:
Attilio Bondanza
Renato Ostuni
Giulia Barbiera
Marco Genua
Margherita Norelli
PROVIDER: E-MTAB-6505 | ArrayExpress | 2018-05-24
REPOSITORIES: ArrayExpress
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