Transcriptomics

Dataset Information

36

RNA-seq of IMR-5/75 neuroblastoma cell line upon TBX2 and/or MYCN knockdown


ABSTRACT: RNA-seq upon TBX2, MYCN or combination of TBX2 and MYCN knockdown in the neuroblastoma cell line IMR-5/75. Cells were transduced with two different shRNAs (shTBX2_2 and shTBX2_4) targeting TBX2 and a non-targeting control (NTC), and selected with puromycin. Cells were treated with doxycycline for shMYCN induction (with DOX or not). Analysis was performed three days upon TBX2 knockdown and two days upon MYCN knockdown, including six biological replicates per condition.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens  

SUBMITTER: Bieke Decaesteker  

PROVIDER: E-MTAB-6568 | ArrayExpress | 2018-08-16

SECONDARY ACCESSION(S): ERP107244

REPOSITORIES: ArrayExpress, ENA

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