Transcriptomics

Dataset Information

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Gene expression profile in human monocytes treated with IgG from APS patients or IgG from controls


ABSTRACT: The antiphospholipid syndrome (APS) is an autoimmune disease in which antiphospholipid antibodies (aPL) cause vascular thrombosis (VT+) and/or pregnancy morbidity (PM+). The experiment aimed at determining whether specific aPL are associated with thrombotic or obstetric manifestations. In the present study we carried out microarray analysis comparing patterns of mRNA expression in monocytes from a healthy volunteer exposed to IgG from patients with a history of vascular thrombosis (VT+/PM-) or pregnancy morbidity (VT-/PM+) or to IgG from healthy controls (HC).

ORGANISM(S): Homo sapiens  

DISEASE(S): Normal

SUBMITTER: Francesca Pregnolato  

PROVIDER: E-MTAB-6671 | ArrayExpress | 2018-04-28

REPOSITORIES: ArrayExpress

Dataset's files

Source:
Action DRS
E-MTAB-6671.idf.txt Idf
E-MTAB-6671.idf.txt_original Idf
E-MTAB-6671.raw.1.zip Raw
E-MTAB-6671.sdrf.txt Txt
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