Transcriptomics

Dataset Information

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A microarray meta-dataset of liver cancer


ABSTRACT: We present a meta-dataset comprising of a total of 401 samples including both primary tumors and tumor-free liver tissues from seven independent GEO datasets. To minimise inter-platform variation, only datasets generated from the GPL570 platform (Affymetrix Human Genome U133 Plus 2.0 Array) were processed to develop the meta-dataset. Using multiple open source R packages implemented in our previously developed bioinformatics pipeline, each dataset has been preprocessed with RMA normalisation, merged, and batch effect-corrected via Combat method. With increased sample size, the present meta-dataset serves an excellent 'discovery cohort' for discovering differentially expressed in diseased phenotype.

ORGANISM(S): Homo sapiens  

SUBMITTER: Su Bin Lim  

PROVIDER: E-MTAB-6695 | ArrayExpress | 2019-04-11

REPOSITORIES: ArrayExpress

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