Transcriptomics

Dataset Information

239

MiR-181b is a biomarker of disease progression in Chronic Lymphocytic Leukemia


ABSTRACT: We studied the value of the microRNAs as a signature for Chronic lymphocytic leukemia (CLL) patients with specific chromosomal abnormalities. We found that MiR-181b is abiomarker of disease progression in Chronic Lymphocytic Leukemia

OTHER RELATED OMICS DATASETS IN: E-TABM-763

ORGANISM(S): Homo sapiens  

DISEASE(S): Chronic Lymphocytic Leukemia

SUBMITTER: Rosa Visone   Cristian Taccioli  

PROVIDER: E-MTAB-683 | ArrayExpress | 2011-09-22

REPOSITORIES: ArrayExpress

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Publications


Chromosomal abnormalities, immunoglobulin heavy chain variable-region (IGHV) gene mutation status, and zeta-associated protein 70 (ZAP-70) expression levels have independent prognostic relevance in chronic lymphocytic leukemia (CLL); however, their concordance is variable. Because deregulation of microRNAs has been linked to disease initiation and progression in CLL, we studied the value of the microRNAs as a signature for CLL patients with specific chromosomal abnormalities. We identified 32 mi  ...[more]

Publication: 1/2

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