Genomics

Dataset Information

34

Nus factors prevent premature transcription termination of bacterial CRISPR arrays


ABSTRACT: We used ChIP-seq to map binding of the CRISPR surveillance complex, Cascade, in a Salmonella enterica serovar Typhimurium strain lacking the gene encoding the endonuclease Cas3. We performed ChIP-seq in strains with wild-type and mutant sequences upstream of the two CRISPR arrays, and in strains with wild-type and mutant nusE genes to determine the impact of Nus factor antitermination on CRISPR array function.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium  

SUBMITTER: Anne M Stringer  

PROVIDER: E-MTAB-7242 | ArrayExpress | 2018-10-13

SECONDARY ACCESSION(S): ERP111085

REPOSITORIES: ArrayExpress, ENA

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